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ASH 2023 | Incidence of COVID-19 infections in vaccinated patients with CLL

Chaitra Ujjani, MD, University of Washington & Fred Hutchinson Cancer Research Center, Seattle, WA, discusses the findings of a prospective observational study (NCT04852822) evaluating the efficacy of the SARS-CoV-2 vaccine in patients with chronic lymphocytic leukemia (CLL). The vaccine induced lower response rates in CLL patients when compared to healthy individuals. Furthermore, infection rates in patients were substantially higher following the booster dose, likely due to less stringent social distancing and masking practices and the emergence of new viral strains. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.

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Disclosures

Consultancy: Lilly, Janssen, Pharmacyclics, Genentech, Beigene, Kite, a Gilead Company, Epizyme, Astrazeneca, Abbvie, Atara; Honoraria: Lilly, Janssen, Pharmacyclics, Genentech, Beigene, Astrazeneca, Abbvie; Research Funding: Lilly, Pharmacyclics, PCYC, Kite, a Gilead Company, Astrazeneca, Abbvie; Travel expenses: Kite, a Gilead Company