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ASCO 2022 | Peak ALC after CAR-T infusion predicts clinical response in aggressive lymphoma

Radhika Bansal, MBBS, Mayo Clinic, Rochester, MN, talks on the association between peak absolute lymphocyte count (ALC) after CAR-T infusion and clinical response in aggressive lymphoma. A higher absolute lymphocyte ALC peak was associated with increased complete response rates and a longer duration of response in the first 6 months post-CAR-T cell infusion. Increasing ALC levels also correlated with CAR-T cell expansion and higher rates of progression-free survival (PFS) and overall-survival (OS). This interview took place at the American Society of Clinical Oncology (ASCO) 2022 Annual Meeting in Chicago, IL.