Paul Richardson, MD, of Dana-Farber Cancer Institute, Boston, MA gives an overview of the session on endothelial damage and transplantation. Prof. Richardson explains that there is an evolving risk model for endothelial stress syndromes and one can rationally consider that various strategies to prevent or reverse them would start to evolve. Recorded at the European Society for Blood and Marrow Transplantation (EBMT) 2019 Annual Meeting, held in Frankfurt, Germany.