Here, Michele Cavo, MD, of Bologna University School of Medicine, Bologna, Italy, discusses a retrospective analysis of three previous European trials which compared bortezomib-based vs. non-bortezomib based transplant regimens for multiple myeloma. This supported the EMN02 trial (NCT01208766) data, which suggested that double transplants provided more benefits than single transplants. This interview was recorded at the Controversies in Multiple Myeloma (COMy) 2019 meeting held in Paris, France.