In this video, Panagiota-Efstathia Nikolaou, PhD, National and Kapodistrian University of Athens, Athens, Greece, discusses the role of free light chains in patients with cardiac AL amyloidosis, and shares some insights into a study which compared the cardiotoxicity of full-length light chains in patients with cardiac AL amyloidosis versus other plasma cell dyscrasias. This interview took place at the 2022 International Symposium on Amyloidosis (ISA) held in Heidelberg, Germany.