Annamaria Brioli, MD, Universitätsklinikum Jena, Jena, Germany, discusses the use of pomalidomide and dexamethasone combinations as salvage therapy for multiple myeloma patients relapsed and/or refractory to daratumumab. This area of research is particularly pertinent, with the use of daratumumab for the treatment of myeloma becoming increasingly widespread. This interview took place during the 2021 European Myeloma Network (EMN) congress.