Nirav N. Shah, MD, Medical College of Wisconsin, Brookfield, WI, talks on adverse events associated with BTK inhibitor therapy. Ibrutinib, acalabrutinib and zanubrutinib are all BTK inhibitors used in the treatment of non-Hodgkin lymphoma. Dr Shah reports that cardiac toxicities are associated with BTK inhibitor therapy, in particular with ibrutinib, and comments on the need to develop drugs which minimise the risk of cardiac toxicities. This interview took place at the virtual European Hematology Association (EHA) Congress 2021.