Big topics for discussion at this year’s ISA meeting include measurable residual disease (MRD) assessment and hematological response measurement in AL amyloidosis. Vaishali Sanchorawala, MD, Boston University School of Medicine, Boston, MA, discusses these hot topics from ISA 2020. This interview was recorded via an online conference call with The Video Journal of Hematological Oncology (VJHemOnc).