Jürgen Kuball MD, PhD, from the University Medical Center, Utrecht, Amsterdam, discusses the potential for CART-cell therapy in solid cancers, as well as the challenges involved in transitioning a treatment designed for hematological cancers to other forms of tumour-based cancers. Recorded at the 1st European CAR T-cell meeting in Paris, France, co-organized by the European Society for Blood & Marrow Transplantation (EBMT) and the European Hematology Association (EHA).