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BSH 2022 | Adult stem cell transplantation for the treatment of SCD

Josh Wright, BMedSci (Hons), MBChB, FRCPath, MD, BSH president, discusses a presentation at BSH 2022 which focused on the use of adult stem cell transplantation for the treatment of sickle cell disease (SCD). Dr Wright further highlights the excitement around this novel treatment approach, and the benefits of being able to offer novel therapeutic options for patients with SCD. This interview took place at the 62nd Annual Scientific Meeting of the British Society for Haematology (BSH) 2022, in Manchester, UK.

Transcript (edited for clarity)

For me, I’m interested to see Victoria Potter’s update on adult stem cell transplantation. That’s a new thing for the UK. Pediatric transplants have been accepted and commissioned for a long time, but adult transplants are a relatively new occurrence for us. It’s a sort of novel conditioning regime. Very much a reduced intensity protocol. And I think if you’d have told me five or 10 years ago that I’d be actively seeking to transplant my patients, I’d have shaken my head and denied it...

For me, I’m interested to see Victoria Potter’s update on adult stem cell transplantation. That’s a new thing for the UK. Pediatric transplants have been accepted and commissioned for a long time, but adult transplants are a relatively new occurrence for us. It’s a sort of novel conditioning regime. Very much a reduced intensity protocol. And I think if you’d have told me five or 10 years ago that I’d be actively seeking to transplant my patients, I’d have shaken my head and denied it. But, I very much am. I mean, it’s a disease which has enormous long term consequences and to be able to offer a cure effectively for this dreadful disease, which we forget has such a poor prognosis, I think, is a tremendous privilege. And I’m delighted to actually be putting through our first patient as well at the moment. So, I’m very interested to hear her update.

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Disclosures

Advisory Board fees for GBT and Vertex Pharma.
Director of BSHE (the commercial arm of BSH)