Krish Patel, MD, Swedish Cancer Institute, Seattle, WA, reports on results from a Phase II trial (NCT03736616) assessing acalabrutinib plus RICE chemotherapy in transplant-eligible, relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL). Acalabrutinib plus RICE was beneficial after three cycles of treatment with respect to overall response (OR) and complete response (CR) rates. Dr Patel also highlights that a high proportion of patients were subsequently able to undergo autologous stem cell transplantation (autoSCT). This interview took place at the 64th ASH Annual Meeting and Exposition congress in New Orleans, LA.
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