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IMS 2026 | Managing CNS-involved myeloma: CAR T-cell access and alternative treatment strategies

Sven Neubert, MD, University Hospital Wuerzburg, Wuerzburg, Germany, discusses treatment considerations for patients with multiple myeloma and central nervous system (CNS) involvement who lack access to CAR T-cell therapy. Dr Neubert emphasizes the importance of early referral to specialist centers, ideally before bridging therapy, and discusses alternative approaches including radiotherapy, systemic treatment, and intrathecal therapy, while acknowledging their limited potential for durable responses. This interview took place at the 23rd International Myeloma Society (IMS) Annual Meeting in Glasgow, UK.

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