Varsha Gandhi, MD, The University of Texas MD Anderson Cancer Center, Houston, TX, presents the key points from a paper she has co-authored, titled ‘Curing chronic lymphocytic leukemia (CLL): one clone at a time’. This paper discusses the use of a strategy in which driver mutations (such as C481S and T474I) in the CLL cell population are not treated simultaneously, but rather sequentially, by sequencing covalent and non-covalent BTK inhibitors (BTKi’s) in a specific manner. This interview was recorded at the biennial International Workshop on Chronic Lymphocytic Leukemia (iwCLL) 2023 meeting, held in Boston, MA.
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