In this interview, Varsha Gandhi, MD, The University of Texas MD Anderson Cancer Center, Houston, TX, summarizes the different strategies for improving efficacy of non-covalent BTK inhibitor (BTKi) treatment. These include using non-covalent BTKi’s in patients who have not been previously treated with covalent BTKi’s, and combining or sequencing agents to resensitize cells and produce improved disease outcomes. This interview was recorded at the biennial International Workshop on Chronic Lymphocytic Leukemia (iwCLL) 2023 meeting, held in Boston, MA.
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