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ASH 2023 | Updates from the KarMMa-3 trial: safety profile of ide-cel in TCE R/R multiple myeloma

Rachid Baz, MD, Moffitt Cancer Center, Tampa, FL, discusses the safety profile of idecabtagene vicleucel (ide-cel) compared to standard regimens in patients with triple-class-exposed (TCE) relapsed/refractory (R/R) multiple myeloma (MM) from the Phase III KarMMa-3 trial (NCT03651128). Dr Baz shares that the trial investigated the frequency of cytopenias, infection risk, and the incidence of second primary malignancies between ide-cel and the standard of care (SoC) treatment. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.

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Disclosures

Research Funding: Regeneron, Pfizer, Karyopharm, Janssen, AbbVie, BMS; Honoraria: GSK, HIKMA Cancer Network, Curio Science, AHOMPR, ASH; Membership on an entity’s Board of Directors or advisory committees: Pfizer, Janssen, BMS.