ASH 2023 | Investigating drivers of non-relapse mortality following CAR-T therapy in hematological malignancies
Kai Rejeski, MD, Memorial Sloan Kettering Cancer Center, New York City, NY, shares the findings of a meta-analysis which investigated drivers of non-relapse mortality (NRM) following CAR-T therapy using data from clinical trials and real-world studies (RWS). Data was obtained for all commercially available CAR-T products, and Dr Rejeski summarizes the differences in NRM rates observed across various disease entities. Interestingly, infections were identified as the major driver of NRM, accounting for almost 50% of events. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.
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Disclosures
Consultancy: BMS/CELGENE
Honoraria: BMS/CELGENE, Novartis
Travel Support: Kite/Gilead, Pierre-Fabre
Research Funding: Kite/Gilead
