Sara Tinsley-Vance, PhD, APRN, Moffitt Cancer Center, Florida, USA, describes the quality of life (QOL) of patients with myelodysplastic syndromes (MDS). Dr Tinsley-Vance explains that although there are tools to measure the QOL, it is highly subjective and it is thus crucial to ask the patient about their own needs. This interview took place at the 16th International Congress on Myelodysplastic Syndromes, held virtually in 2021.