Bob Löwenberg, MD, PhD, of Erasmus University Medical Centre, Rotterdam, Netherlands, discusses developments in newly diagnosed acute myeloid leukemia (AML) therapy in Europe from the International Symposium on Acute Leukemias (ISAL) 2019, held in Munich, Germany. Prof. Löwenberg explains how these new therapies may replace or add value to the standard 7+3 chemotherapy backbone, and highlights the need for multinational cooperation to recruit sufficient numbers of patients to trials.