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ASCO 2022 | Prognostic value of early bone marrow MRD status in CAR-T therapy for myeloma

Radhika Bansal, MBBS, Mayo Clinic, Rochester, MN, discussses the results of a retrospective study evaluating the use of bone marrow assessment of minimal residual disease (MRD) as a surrogate endpoint in patients with multiple myeloma receiving CAR T-cell therapy. Bone marrow MRD negativity was associated with prolonged survival and those who were MRD positive at 1 month were highly unlikely to convert to MRD negative. This interview took place at the American Society of Clinical Oncology (ASCO) 2022 Annual Meeting in Chicago, IL.