Petri Pölönen, PhD, St. Jude’s Research Hospital, Memphis, TN, briefly explains the need to improve diagnostic tools in T-cell acute lymphoblastic leukemia (T-ALL), highlighting the importance of using whole genome sequencing (WGS) and transcriptome sequencing to obtain genomic information.This interview took place at the European Hematology Association (EHA) Congress 2022 held in Vienna, Austria.