Sigrun Thorsteinsdottir, MD, National University Hospital of Iceland, Reykjavik, Iceland, discusses the potential impact of the ongoing iStopMM study assessing the benefits and harms of screening the general population for smoldering multiple myeloma (NCT03327597). Dr Thorsteinsdottir explains that if the study finds that screening positively impacts overall survival (OS) and quality of life (QoL), it could be introduced into clinical practice. This interview took place at the 63rd ASH Annual Meeting and Exposition congress in Atlanta, GA.