Noemí Puig, MD, PhD, University Hospital Salamanca, Salamanca, Spain, discusses outcomes from the observational, global INSIGHT-MM study (NCT02761187) which has analysed data from 821 patients with relapsed/refractory (R/R) multiple myeloma from 15 countries in order to asses the duration of treatment (DOT) with lenalidomide-dexamethasone (Rd)-based regimens. Dr Puig gives an overview of the rationale for the study and summarizes the key findings. This interview took place at the virtual European Hematology Association (EHA) Congress 2021.