Raphael Itzykson, MD, PhD, Saint-Louis Hospital AP-HP, Paris, France, outlines the results of a Phase II study investigating eltrombopag, a thrombopoietin receptor agonist, for patients with chronic myelomonocytic leukemia (CMML) and thrombocytopenia. The study found that treatment with eltrombopag was safe for CMML patients with severe thrombocytopenia and no marrow blast excess, and could thus help manage a situation at risk of bleeding such as a scheduled surgical procedure. This interview took place during the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition, 2020.