Bruno Paiva, PhD, University of Navarra, Pamplona, Spain, discusses three important assets of measurable residual disease (MRD) in multiple myeloma. First that MRD has emerged as one of the most relevant diagnostic factors for myeloma. Second, that undetectable MRD in a significant proportion of patients could become a treatment endpoint. Third, that MRD response will be a surrogate for survival and a potential biomarker. This interview took place during the Controversies in Multiple Myeloma (COMy) 2020 Virtual World Congress.