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SOHO 2022 | Using MRD and mutational analysis when selecting patients with T-ALL for transplantation

Josep-Maria Ribera, MD, PhD, University of Barcelona, Barcelona, Spain, explains which T-cell acute lymphoblastic leukemia (T-ALL) patient subgroups should be considered for allogeneic transplantation, including those who are measurable residual disease (MRD) positive after induction or consolidation therapy and those with early T-cell precursor (ETP) T-ALL. Prof. Ribera also comments on key mutations which influence indication for transplantation, such as RAS and absence of NOTCH-1. This interview took place at the Tenth Annual Meeting of the Society of Hematologic Oncology (SOHO) held in Houston, TX.

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