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ASH 2022 | Potent pre-clinical and early phase activity of inobrodib in multiple myeloma

Tim Somervaille, PhD, FRCP, FRCPath, The University of Manchester, UK, discusses the pre-clinical and early phase clinical activity of inobrodib, a novel bromodomain inhibitor, for the treatment of multiple myeloma. Pre-clinical studies have demonstrated promising activity, and Dr Somervaille highlights an ongoing early Phase I/IIa trial (NCT04068597) exploring this agent in patients with various hematological malignancies. Inobrodib is also being evaluated in combination with pomalidomide, which has demonstrated promising efficacy. This interview took place at the 64th ASH Annual Meeting and Exposition congress in New Orleans, LA.

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Abbvie: Consultancy; Novartis: Consultancy; Bristol Myers Squibb: Consultancy; Imago Biosciences: Research Funding; Oryzon Genomics: Consultancy; CellCentric Ltd: Research Funding.