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EHA 2024 | Does a reduced dosing frequency of carfilzomib affect outcomes for patients with R/R myeloma?

Rahul Banerjee, MD, FACP, Fred Hutchinson Cancer Center, Seattle, WA, discusses an analysis of real-world data that aimed to investigate carfilzomib prescribing patterns in relapsed/refractory (R/R) multiple myeloma (MM) and how these have changed over time. In the United States, once-weekly carfilzomib dosing has become the norm, with Dr Banerjee emphasizing that this does not impact the progression-free survival (PFS) of patients. A decrease in the dosing frequency of the agent comes with the benefit of decreased time toxicity, as patients do not have to visit the clinic several times per week. This interview took place at the 29th Congress of the European Hematology Association (EHA) in Madrid, Spain.

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Disclosures

Consultancy: Adaptive Biotechnologies, Bristol-Myers Squibb/Celgene, Caribou Biosciences, Genentech, GlaxoSmithKline, Janssen, Karyopharm Therapeutics, Legend Biotech, Pfizer, Sanofi, SparkCures; Research Funding: Abbvie, Bristol-Myers Squibb/Celgene, Janssen, Novartis, Pack Health/Quest Diagnostics, Prothena, Sanofi.