In this video, Prithviraj Bose, MBBS, The University of Texas MD Anderson Cancer Center, Houston, TX, shares some insights into the recent approval of pemigatinib for the treatment of patients with relapsed/refractory (R/R) myeloid/lymphoid neoplasms with FGFR1 rearrangement. Dr Bose highlights the challenges of treating these patients and further explains the impact of this approval in the field. This interview took place at the third annual Texas MPN Workshop (TMW) 2022, held in San Antonio, TX.