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ASH 2023 | Management of patients with penta-class refractory myeloma

Amrita Krishnan, MD, City of Hope, Duarte, CA, emphasizes the importance of understanding the underlying reasons for patients with multiple myeloma (MM) becoming penta-class refractory in order to address the unmet treatment need for this patient population. Refractoriness may stem from a loss of target or compromised T-cell health, so targeting different markers or administering drugs to restore T-cell fitness are potential strategies to overcome this. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.

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Stock Options/Ownership-Public Company: Bristol-Myers Squibb Company
Speakers Bureau: Amgen Inc, Bristol-Myers Squibb Company, Takeda Pharmaceuticals USA Inc
Contracted Research: Janssen Biotech
Consultancy: Adaptive Biotechnologies Corporation, Bristol-Myers Squibb Company, GlaxoSmithKline, Regeneron Pharmaceuticals Inc, Sanofi Genzyme
Advisory Committee: Sutro Biopharma