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EHA 2026 | Results from the EPO-Pretar trial: impact of early vs delayed ESA initiation in patients with LR-MDS

Sophie Park, MD, PhD, CHU Grenoble Alpes, Grenoble, France, discusses results from the Phase III EPO-Pretar trial (NCT03223961) investigating the impact of early versus delayed ESA initiation in patients with lower-risk myelodysplastic syndromes (LR-MDS). Dr Park highlights that although there was no difference in transfusion dependence between the early and delayed arms, the erythroid response rate was higher in the early arm (85% versus 55%). She also comments on the use of the ESA-IPSS-M score to calculate a patient’s response duration to ESAs. This interview took place at the 31st Congress of the European Hematology Association (EHA) in Stockholm, Sweden.

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