Joan Bladé, MD, PhD, University of Barcelona, Barcelona, Spain, briefly discusses how the amyloidosis treatment landscape has transformed with the addition of daratumumab to cyclophosphamide, bortezomib, and dexamethasone, and the exciting implications that this combination therapy has for the future of amyloidosis treatment. This interview took place at the 8th World Congress on Controversies in Multiple Myeloma (COMy) 2022, held in Paris, France.