Jennifer Woyach, MD, Ohio State University College of Medicine, Columbus, OH, shares the results of a Phase I study of nemtabrutinib, a non-covalent BTK inhibitor in patients with relapsed/refractory (R/R) chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL; NCT03162536). Whilst the initial results appear promising, with high response rates, a longer follow-up is required to evaluate the durability of response to this drug. This interview took place at the European Hematology Association (EHA) Congress 2022 held in Vienna, Austria.