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IMS 2026 | Mezigdomide in combination with carfilzomib and dexamethasone (MeziKd) in relapsed myeloma

Meletios Dimopoulos, MD, Kapodistrian University of Athens School of Medicine, Athens, Greece, discusses the Phase II/III SUCCESSOR-2 (NCT05552976) results evaluating mezigdomide in combination with carfilzomib and dexamethasone (MeziKd) in heavily pretreated relapsed or refractory multiple myeloma. He highlights a doubling of progression-free survival (PFS) compared with carfilzomib and dexamethasone, supporting the potential of this outpatient regimen in relapsed disease. This interview took place at the 23rd International Myeloma Society (IMS) Annual Meeting in Glasgow, UK.

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