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IMS 2022 | CARTITUDE-2 update: cilta-cel in relapsed and lenalidomide-refractory patients with multiple myeloma

Adam Cohen, MD, University of Pennsylvania, Philadelphia, PA, gives an update on the results of Cohort A from the CARTITUDE-2 trial (NCT04133636). Dr Cohen explains that in this patient population who has received 1-3 prior lines of treatment and is lenalidomide-refractory, ciltacabtagene autoleucel (cilta-cel) appeared to have promising durability and safety. The results of this study have led to the ongoing CARTITUDE-4 trial (NCT04181827) comparing cilta-cel vs standard triplet therapies in patients with relapsed and lenalidomide-refractory multiple myeloma. This interview took place at the 19th International Myeloma Society Meeting (IMS) held in Los Angeles, CA.

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