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ASH 2022 | Using drug class refractoriness to classify patients with R/R myeloma receiving modern therapy

Luciano Costa, MD, PhD, UAB School of Medicine, Birmingham, AL, discusses using drug class refractoriness, rather than number of prior lines of therapy (LOT), to classify patients with multiple myeloma (MM) undergoing therapy. It was found that in patients receiving modern therapy for relapsed/refractory (R/R) myeloma, drug class refractoriness predicted overall response rate (ORR) and progression-free survival (PFS) more accurately, and Dr Costa explains the importance of using these findings when selecting patients for clinical trials and treatment with novel agents. This interview took place at the 64th ASH Annual Meeting and Exposition congress in New Orleans, LA.

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Disclosures

Sanofi: Consultancy, Honoraria; Adaptive Biotechnologies: Consultancy, Honoraria; Bristol Myers Squibb: Consultancy, Honoraria, Research Funding; Genentech: Research Funding; AbbVie: Research Funding; Amgen: Consultancy, Honoraria, Research Funding; Janssen: Consultancy, Honoraria, Research Funding.