Noffar Bar, MD, Yale School of Medicine, New Haven, CT, discusses an unanchored matching-adjusted indirect comparison (MAIC) of ciltacabtagene autoleucel (cilta-cel) and idecabtagene vicleucel (ide-cel) in patients with relapsed/refractory (R/R) multiple myeloma (MM) who have been treated with 2-4 prior lines of therapy. The MAIC used data from three clinical trials investigating these CAR T-cell therapies: CARTITUDE-1 (NCT03548207), CARTITUDE-4 (NCT04181827), and KarMMa-3 (NCT03651128) to compare efficacy and patient outcomes. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.
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