Evangelos Terpos, MD, PhD, from the University of Athens, School of Medicine, Athens, Greece, discusses the Endeavour study (NCT01568866) at the 2017 World Congress on Controversies in Multiple Myeloma (COMy) in Paris, France. This study compared the progression free survival of dexathasone combined with bortezomib or carfilzomib. The key finding of this study was that dexamethasone plus carfilzomib produced an overall survival advantage, in comparison to dexamethasone plus botezomib.