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ASH 2019 | MRD-driven immunotherapy in early stage follicular lymphoma

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Alessandro Pulsoni

Alessandro Pulsoni, MD, Sapienza University of Rome, Rome, Italy, outlines the FIL_MIRO study (NCT02710643). This phase II, multicenter trial combines local radiotherapy and measurable residual disease (MRD) driven immunotherapy in early stage follicular lymphoma. The first results of the study show that MRD negativity after immunotherapy with an anti-CD20 monoclonal antibody, ofatumumab, was achieved. Prof. Pulsoni mentions that a longer follow-up will allow to conclusively define the impact of the MRD-driven strategy on clinical outcome. This interview took place at the American Society of Hematology (ASH) 2019 Annual Meeting and Exposition in Orlando, FL.

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