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ASH 2021 | PACIFIC: Brentuximab vedotin in mediastinal DLBCL
Jason Westin, MD, FACP, University of Texas MD Anderson Center, Houston, TX, describes the trial design of the Phase II PACIFIC trial (NCT04745949) of brentuximab vedotin, an antibody-drug conjugate (ADC), in patients with stage I-IV primary mediastinal diffuse large B-cell lymphoma (DLBCL). The trial aims to evaluate immunotherapy in the frontline setting as an alternative to chemotherapy in patients with mediastinal DLBCL, which will reduce the toxicity experienced by patients. This interview took place at the 63rd ASH Annual Meeting and Exposition congress in Atlanta, GA.
