Arnon Nagler, MD, Chaim Sheba Medical Center, Tel-Aviv, Israel, gives an overview of the topics discussed during the COMy 2020 meeting. The main areas of discussion this year were smoldering myeloma, new drugs approved for multiple myeloma, CAR T-cell therapies and new monoclonal antibodies. The role of MRD in multiple myeloma was also discussed. The meeting this year was very successful with attendees from over 100 countries and thousands of people watching. This interview took place during the Controversies in Multiple Myeloma (COMy) 2020 Virtual World Congress.