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EHA 2023 | Advances in BTK and BCL2 inhibitors for CLL

Jennifer Brown, MD, PhD, Dana-Farber Cancer Institute, Boston, MA, gives an overview of the latest advances in the field of BTK and BCL2 inhibitors, commenting on first- and second-generation BTK inhibitors as well as BTK degraders, novel BCL2 inhibitors, and the potential of combination and time-limited therapies. This interview took place at the 28th Congress of the European Hematology Association (EHA) 2023 in Frankfurt, Germany.

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Disclosures

JRB has served as a consultant for Abbvie, Acerta/Astra-Zeneca, Alloplex Biotherapeutics, BeiGene, Genentech/Roche, Grifols Worldwide Operations, Hutchmed, iOnctura, Janssen, Kite, Loxo/Lilly, Merck, Numab Therapeutics, Pfizer, Pharmacyclics; received research funding from BeiGene, Gilead, iOnctura, Loxo/Lilly, MEI Pharma, SecuraBio, TG Therapeutics.