Luciano Costa, MD, PhD, UAB School of Medicine, Birmingham, AL, presents the first interim results of the MajesTEC-3 trial (NCT05083169), a Phase III randomized study comparing teclistamab plus daratumumab (Tec-Dara) to investigator’s choice of daratumumab and dexamethasone with either pomalidomide or bortezomib (DPd/DVd) in patients with relapsed/refractory (R/R) multiple myeloma (MM) who have received 1–3 prior lines of therapy. Dr Costa notes that the safety and efficacy data to date are highly encouraging and believes that Tec-Dara may represent a new standard of care in myeloma from the second-line setting and beyond. This interview took place at the 67th ASH Annual Meeting and Exposition, held in Orlando, FL.
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