Sagar Lonial, MD, FACP, Winship Cancer Institute at Emory University, Atlanta, GA, discusses the the latest translational and clinical evidence for iberdomide (CC-220), a novel cereblon E3 ligase modulatory compound (CELMoD), from preclinical data and a current phase 1/2 trial in relapsed/refractory myeloma (NCT02773030). This interview took place at the American Society of Hematology (ASH) 2019 Annual Meeting and Exposition in Orlando, FL.