Ilaria Iacobucci, PhD, St. Jude Children’s Research Hospital, Memphis, TN, comments on the Philadelphia chromosome (Ph)-like subtype of acute lymphoblastic leukemia (ALL), and highlights the challenges that remain in diagnosing and guiding treatment of patients with Ph-like ALL. Dr Iacobucci discusses the need for comprehensive characterization of the disease, particularly through transcriptome profiling. This interview took place at the Eleventh Annual Meeting of the Society of Hematologic Oncology (SOHO 2023) held in Houston, TX.
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