ASH 2022 | Phase Ib trial of acalabrutinib + rituximab with or without lenalidomide in R/R follicular lymphoma
Paolo Strati, MD, The University of Texas MD Anderson Cancer Center, Houston, TX, discusses a Phase Ib trial of the bruton tyrosine kinase (BTK) inhibitor, acalabrutinib, plus rituximab and lenalidomide in patients with relapsed or refractory (R/R) follicular lymphoma (FL). The efficacy of acalabrutinib was reported to improve when combined with rituximab and lenalidomide, and adverse events were infrequent and low-grade. This interview took place at the 64th ASH Annual Meeting and Exposition congress in New Orleans, LA.
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Disclosures
Hutchinson MediPharma: Consultancy; ADC Therapeutics: Consultancy, Research Funding; TG Therapeutics: Consultancy; Kite Gilead: Consultancy; Astrazeneca Acerta: Research Funding; ALX Oncology: Research Funding; Sobi: Research Funding; Roche Genentech: Consultancy.
