In this video, Mattia D’Agostino, MD, University of Turin, Turin, Italy, shares some insights into current and future treatment approaches in multiple myeloma, and the excitement around bringing novel agents to the frontline setting. Dr D’Agostino also highlights treatment options for transplant-eligible and elderly patients, and concludes by mentioning the promise of immunotherapies, including CAR-T therapy and bispecific antibodies. This interview took place at the 8th World Congress on Controversies in Multiple Myeloma (COMy) 2022, held in Paris, France.