Patient-reported outcomes provide health information directly from the patient and may aid in hematopoietic stem-cell transplantation (HSCT) prognostication. In this video, Hélène Schoemans, MD, University of Leuven, Leuven, Belgium, discusses the use of patient-reported outcomes in HSCT. This interview took place during the 47th Annual Meeting of the European Group for Blood and Marrow Transplantation (EBMT) 2021.