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ASH 2023 | Efficacy of D-RVD vs RVD in patients with newly diagnosed t(11;14) multiple myeloma

Jonathan Kaufman, MD, Emory University School of Medicine, Atlanta, GA, provides the highlights from a study looking at a real-world comparison of patients with t(11;14) multiple myeloma (MM) treated with either lenalidomide, bortezomib, and dexamethasone (RVD) or daratumumab+RVD (D-RVD) induction therapy and assessing response and outcomes. The study aimed to address whether adding daratumumab to RVD confers a treatment benefit in patients with newly-diagnosed MM. In this cohort, the addition of daratumumab improved the very good partial response (VGPR) rate and progression-free survival (PFS). This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.

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Disclosures

Consultancy: Abbvie, Incyte, BMS, Sanofi