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CAR-T Meeting 2026 | T2EVOLVE and GoCART harmonization to create alignment in European CAR-T data collection

In this video, Carmen Sanges, PhD, University Hospital Würzburg, Würzburg, Germany, discusses the T2EVOLVE and GoCART harmonization efforts, highlighting the importance of synergizing initiatives across Europe to align CAR-T data collection. This interview took place at the EBMT-EHA 8th European CAR T-cell Meeting, held in Palma de Mallorca, Spain.

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Transcript

This is an example, a great example, on how T2EVOLVE acts and integrates initiatives across Europe. We synergized already with GoCART in the project time, when we realised that the data is actually something that constitutes a hurdle across Europe in terms of harmonization. When the CAR-T therapy hype began a few years ago, the data collection was not yet harmonized, not even in one country alone, not even between different institutes that were delivering the therapy...

This is an example, a great example, on how T2EVOLVE acts and integrates initiatives across Europe. We synergized already with GoCART in the project time, when we realised that the data is actually something that constitutes a hurdle across Europe in terms of harmonization. When the CAR-T therapy hype began a few years ago, the data collection was not yet harmonized, not even in one country alone, not even between different institutes that were delivering the therapy. At this point, we realized that there was really a barrier in comparing the data generated by this innovative technology and that learning from the technology was basically impossible. So we did a step back in synergy with GoCART and we really wanted to set the backbone, the right backbone for the data collection and the possibility to make this data interoperable as soon as possible. And this is a great example of what we have done together in the past year, but also we will continue during the association time to sustain the achievements. Like for example, the consensus-driven core CAR-T dataset that we put together with a Delphi survey that was pan-European as well, and the OMOP of the Datadi National Registry in Austria, that is now a blueprint branded T2EVOLVE and GoCART.

 

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