Luciano Costa, MD, PhD, UAB School of Medicine, Birmingham, AL, discusses the implications of a rise in measurable residual disease (MRD) levels in patients with newly diagnosed multiple myeloma (NDMM) treated with quadruplet therapy and autologous stem cell transplantation (autoSCT). In a cohort of over 200 patients, it was found that a tenfold increase in MRD is a reliable indicator of disease progression, challenging the current paradigm. This interview took place at the 66th ASH Annual Meeting and Exposition, held in San Diego, CA.
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